Nioh 3 Mezuki Boss Guide

Horse-headed yokai with massive weapon

Cursed Blossoms Village
Difficulty ★★★★★
Level 25+
Weakness: Fire / Lightning

Boss Overview

Mezuki is a horse-headed yokai that wields a massive weapon with devastating power. It appears in the Cursed Blossoms Village area. While its attacks are slow, each strike deals tremendous damage and has wide reach. This boss teaches players the importance of patience and precise timing.

Characteristics

  • High Damage: Every attack deals massive damage
  • Slow Attacks: Telegraphed moves but punishing
  • Wide Reach: Large weapon with extensive range
  • Recovery Frames: Long recovery after attacks

Weakness & Preparation

Attribute Weaknesses

Fire

Damage over time, wears down HP

Lightning

Paralysis can interrupt attacks

Recommended Items

  • Fire Talismans: Primary damage source
  • Lightning Talismans: Interrupt attacks
  • Quick-Change Scrolls: Essential for mistakes
  • Paralysis Ammunition: Stop combo chains
  • Elixirs: Keep HP high, one-shot risk

Recommended Guardian Spirits

  • Spirits with Fire or Lightning attributes
  • Spirits providing defense or survival bonuses

Attack Patterns

Overhead Slam
Description: Massive overhead strike with weapon
Counter: Dodge sideways at last moment
Horizontal Sweep
Description: Wide horizontal swing
Counter: Dodge through or backward
Charge Attack
Description: Running charge with weapon strike
Counter: Dodge perpendicular to charge direction
Spin Attack
Description: 360-degree spin with weapon
Counter: Create distance or perfect dodge through
Stomp
Description: Ground stomp creating shockwave
Counter: Jump or dodge away, avoid ground

Combat Strategy

Phase 1 (100% - 70% HP)

  • Learn attack telegraphs, each has clear wind-up
  • Use Low Stance for mobility and quick hits
  • Get 1-2 hits after each attack, then retreat
  • Apply Fire for constant damage over time

Phase 2 (70% - 40% HP)

  • Attack speed slightly increases
  • Begins using charge attack more frequently
  • Switch to Medium Stance for better balance
  • Use Lightning to interrupt big attacks

Phase 3 (40% - 0% HP)

  • Enter berserk mode with faster attacks
  • Spin attack becomes more common
  • Prioritize survival over damage
  • Wait for major recovery windows to attack

General Tips

  • One mistake can be fatal, always play safe
  • Burst Counter is highly recommended
  • Watch stamina, don't exhaust during attack windows
  • Perfect dodge through attacks for ki damage

Recommended Builds

Lightning Sword Build

S-Tier

Weapon: Sword (Lightning enchantment)

Difficulty: Easy

Sword's quick strikes apply paralysis reliably. Safe distance plus burst counter opportunities.

Onmyo Switchglaive Build

S-Tier

Weapon: Switchglaive (Fire/Lightning)

Difficulty: Medium

Elemental talismans with switchglaive reach. Keep applying status effects while staying safe.

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